Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Amino-4-methylphenyl)methanol → N-(5-Hydroxymethyl-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Amino-4-methylphenyl)methanol | HCID 586243 | — |
| 반응물 | 1-Adamantaneacetyl chloride | HCID 2771882 | — |
| 생성물 | N-(5-Hydroxymethyl-2-methylphenyl)-tricyclo[3.3.1.13,7]decane-1-acetamide | HCID 20660024 | 37.3% |
반응 단계
Prepared according to the method of Example 1b) from 1-adamantaneacetyl chloride (2.0 g) and 3-amino4-methylbenzyl alcohol (1.29 g). Silica gel chromatography, eluting with 5% ethylacetate in dichloromethane gave the title compound as a white solid (1.10 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06242470B1 |
| 출처 데이터셋 | uspto-grants-2001_06 |
| ORD ID | ord-f25aab50032645d3957dc2962eedf142 |
| 출처 메모 | uspto-grants-2001_06 |