Oxalyl chloride → Thiophene-2-sulfonyl isocyanate

HRID 1066358노트

반응식

HRID 1066358 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([NH-:9])(=[O:8])=[O:7].C(Cl)(=O)[C:11](Cl)=[O:12]>ClCCCl>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([N:9]=[C:11]=[O:12])(=[O:8])=[O:7]

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 865853752-Thiophenesulfonylamide

생성물 1

HCID 12875192Thiophene-2-sulfonyl isocyanate

시약·촉매·용매 1

HCID 111,2-Dichloroethane용매

실험 절차

A mixture of 2-thiophenesulfonylamide (1.5 g) and oxalyl chloride (6 mL) in 10 mL of 1,2-dichloroethane was refluxed for 14 h. The solvent was removed under vacuum and the crude used as is for the next step.

후처리

  1. temperaturewas refluxed for 14 h
  2. customThe solvent was removed under vacuum

출처 및 근거

ORD 기록
ord-c87843ceab0f4afe83f985e1c0d6e408
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06242493B1

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