Ethyl 3-phenylprop-2-enoate → ethyl (2E)-3-(5-fluoro-2-methylphenyl)prop-2-enoate

반응식

[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:10])=[C:6]([CH:9]=1)[CH:7]=O.[C:11]([O:21][CH2:22][CH3:23])(=[O:20])[CH:12]=CC1C=CC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:10])=[C:6](/[CH:7]=[CH:12]/[C:11]([O:21][CH2:22][CH3:23])=[O:20])[CH:9]=1

참가 물질

반응물 2

HCID 7649Ethyl 3-phenylprop-2-enoate

HCID 27590125-Fluoro-2-methylbenzaldehyde

생성물 1

HCID 131722610ethyl (2E)-3-(5-fluoro-2-methylphenyl)prop-2-enoate

실험 절차

5-Fluoro-2-methylbenzaldehyde (40.58 g; 294 mmol) was converted to the ethyl cinnamate according to step 1 of example 1 to yield 40.81 g. of the title compound.

후처리

customto yield 40.81 g

출처 및 근거

ORD 기록: ord-f894d52001624444b21539639d2bc9af
출처 데이터셋: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06242493B1

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