Dichloromethane → 1-(5-chlorothiophen-2-ylmethyl)3-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine

반응식

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][n:16]([CH2:23][c:24]3[s:25][c:26]([Cl:29])[cH:27][cH:28]3)[c:17]3[n:18][cH:19][cH:20][cH:21][c:22]23)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:30][CH2:31][Cl:32].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][n:16]([CH2:23][c:24]3[s:25][c:26]([Cl:29])[cH:27][cH:28]3)[c:17]3[n:18][cH:19][cH:20][cH:21][c:22]23)[CH2:12][CH2:13]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 688942864-[1-(5-chlorothiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-piperidine-1-carboxylic acid tert-butyl ester

생성물 1

HCID 179729751-(5-chlorothiophen-2-ylmethyl)3-piperidin-4-yl-1H-pyrrolo[2,3-b]pyridine

출처 및 근거

ORD 기록: ord-4fc0ebcf067842db92da7c126fa97d6f
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…