(5-(1-Hydroxy-1-methyl-ethyl))-pyridine-2-sulfonic acid amide → 2-Pyridinesulfonamide, 5-(1-methylethenyl)-

HRID 1066506

반응식

HRID 1066506 반응식
O[C:2]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[N:9][CH:10]=1)([CH3:4])[CH3:3]>C(C(O)=O)(F)(F)F>[C:2]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[N:9][CH:10]=1)([CH3:4])=[CH2:3]

참가 물질

3

반응물 1

HCID 54360667(5-(1-Hydroxy-1-methyl-ethyl))-pyridine-2-sulfonic acid amide

생성물 1

HCID 450806412-Pyridinesulfonamide, 5-(1-methylethenyl)-

시약·촉매·용매 1

HCID 6422Trifluoroacetic acid용매

실험 절차

A solution of 0.1 g of (5-(1-hydroxy-1-methyl-ethyl))-pyridine-2-sulfonic acid amide, product of example 14 b), in CF3CO2H (2 ml) was refluxed for 20 h. The solvent was then removed in vacuo to give 5-isopropenyl-pyridine-2-sulfonic acid amide as a white solid which was essentially pure. EI mass spectrum, m/e 198 (M calculated for C8H10N2O2S: 198).

후처리

  1. customThe solvent was then removed in vacuo

출처 및 근거

ORD 기록
ord-c62a12896c1847b89333b862e90fd174
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06242601B1

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