Ammonia → Octyl 4'-hydroxy-4-biphenylcarboxylate

HRID 1066545노트

반응식

HRID 1066545 반응식
COC([O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)=O.N.ClCCl>C(O)C>[OH:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:19])=[CH:14][CH:13]=2)=[CH:10][CH:11]=1

참가 물질

5

반응물 3

HCID 222AmmoniaHCID 6344DichloromethaneHCID 18328376Octyl4'-methoxycarbonyloxy-4-biphenylcarboxylate

생성물 1

HCID 14692993Octyl 4'-hydroxy-4-biphenylcarboxylate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of compound 5 (5.25 g, 0.014 mol) and aqueous ammonia (35% w/v, 100 ml) in ethanol (200 ml) was stirred for 1 h at room temperature. TLC analysis (dichloromethane) revealed a complete reaction. The solvent was removed in vacuo and the shite solid was recrystallised from ethanol to give colourless crystals.

후처리

  1. customa complete reaction
  2. customThe solvent was removed in vacuo
  3. customthe shite solid was recrystallised from ethanol
  4. customto give colourless crystals

출처 및 근거

ORD 기록
ord-4c0928ed998b44f0abc8a9f40a5bde1b
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06242636B1

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