Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Iodide → [1,1'-Biphenyl]-4-carbonitrile, 4'-(decyloxy)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Iodide | HCID 4875 | — |
| 반응물 | 1-Bromodecane | HCID 8173 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4'-Hydroxy-4-biphenylcarbonitrile | HCID 140610 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | [1,1'-Biphenyl]-4-carbonitrile, 4'-(decyloxy)- | HCID 112405 | — |
반응 단계
A mixture of 4-cyano-4′-hydroxybiphenyl (56) (10.10 g, 0.052 mol), 1-bromodecane (14.38 g, 0.065 mol), anhydrous potassium carbonate (37.32 g, 0.27 mol), butanone (300 ml) and a trace of potassium iodide was heated under reflux overnight. The cooled solution was filtered to remove inorganic salts and the solvent was removed in vacuo. The residual oil was distilled (to remove excess bromide) and finally purified by column chromatography (dichloromethane) to yield a colourless, low melting solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06242636B1 |
| 출처 데이터셋 | uspto-grants-2001_06 |
| ORD ID | ord-ea967d401430401aabcbd2daa2c4c497 |
| 출처 메모 | uspto-grants-2001_06 |