Pyridine → HCID 21195520, 화합물

HRID 1066705노트

반응식

HRID 1066705 반응식
[CH3:1][C:2]1[C:3]([N+:12]([O-:14])=[O:13])=[C:4]([C:8]([CH3:11])=[CH:9][CH:10]=1)[C:5](O)=[O:6].S(Cl)([Cl:17])=O.N1C=CC=CC=1>C1C=CC=CC=1>[CH3:1][C:2]1[C:3]([N+:12]([O-:14])=[O:13])=[C:4]([C:8]([CH3:11])=[CH:9][CH:10]=1)[C:5]([Cl:17])=[O:6]

참가 물질

5

반응물 3

HCID 1049PyridineHCID 24386Thionyl ChlorideHCID 2676503,6-Dimethyl-2-nitrobenzoic acid

생성물 1

HCID 21195520HCID 21195520, 화합물

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

3,6-Dimethyl-2-nitrobenzoic acid in an amount of 9.6 g (51 mmol) was dissolved in 100 ml benzene and then followed by an addition of thionyl chloride in an amount of 8.8 g (74 mmol) and pyridine in an amount of 0.1 lg. The mixture was then heated for 2 hours under reflux, and the solvent therein was distillated out under reduced pressure to obtain 3,6-dimethyl-2-nitrobenzoyl chloride in an amount of 10.3 g.

후처리

  1. temperatureThe mixture was then heated for 2 hours
  2. temperatureunder reflux

출처 및 근거

ORD 기록
ord-e0d45bf9cdb147f8bf56b389bd5c5555
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06245716B1

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