Trifluoroacetic acid → 4-[(2-Fluorophenyl)methoxy]-N-(1-methylethyl)-1-butanamine
반응식
[F:1][C:2]1[CH:24]=[CH:23][CH:22]=[CH:21][C:3]=1[CH2:4][O:5][CH2:6][CH2:7][CH2:8][CH2:9][N:10](C(OC(C)(C)C)=O)[CH:11]([CH3:13])[CH3:12].FC(F)(F)C(O)=O>C(Cl)Cl>[F:1][C:2]1[CH:24]=[CH:23][CH:22]=[CH:21][C:3]=1[CH2:4][O:5][CH2:6][CH2:7][CH2:8][CH2:9][NH:10][CH:11]([CH3:12])[CH3:13]참가 물질
4
실험 절차
The desired intermediate was prepared from the deprotection of 4-(2-fluorobenzyloxy)-N-(t-butoxycarbonyl)-N-(isopropyl)butylamine using standard techniques. The 4-(2-fluorobenzyloxy)-N-(t-butoxycarbonyl)-N-(isopropyl)butylamine was admixed with a 4:1 mixture of methylene chloride and trifluoroacetic acid. The progress of the reaction was monitored by thin layer chromatography.
출처 및 근거
- ORD 기록
- ord-00ccd20f8551458fb74118132f447919
- 출처 데이터셋
- uspto-grants-2001_06
- 특허 번호
- US06245761B1
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