참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | Dibenz(b,f)azepine | HCID 9212 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Phosphoric Acid | HCID 1004 | — |
| 생성물 | Carbamazepine | HCID 2554 | — |
반응 단계
To a suspension of urea (80 g, 1.333 mols) in acetic acid (100 ml), phosphoric acid (8 ml) was added, followed by iminostilbene (20 g, 0.103 mols), under stirring at 25-30° C. The resulting reaction mixture was worked up according to the method of Example 1 to produce carbamazepine, which was identical to the product of Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06245908B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_06 |
|---|
| ORD ID | ord-4ac90fca99bf43eb8cf1417bbe33bd96 |
|---|
| 출처 메모 | uspto-grants-2001_06 |
|---|
