Ammonium dithiocarbamate → Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate

HRID 1067404

반응식

HRID 1067404 반응식
[CH2:1]([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[C:16]2[CH2:15][CH2:14][CH2:13][C:12](=O)[C:11]=2[CH:10]=[CH:9][C:8]=1Br)[CH3:2].[C:20](=[S:23])([S-:22])[NH2:21].[NH4+]>C(O)C>[CH2:1]([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:16]=1[CH2:15][CH2:14][C:13]1[S:22][C:20]([SH:23])=[N:21][C:12]=12)[CH3:2]

참가 물질

4

반응물 2

HCID 11083854Ammonium dithiocarbamateHCID 21193671Ethyl [(2-bromo-5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxy]acetate

생성물 1

HCID 178472952Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate수율 76%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of ethyl[(2-bromo-5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxy]acetate (2.63 g, 8.04 mmol), ammonium dithiocarbamate (1.06 g, 9.60 mmol), and ethanol (30 mL) was refluxed for 14 hours. After cooling, the solid precipitate was recovered by filtration to provide 1.96 g of the title compound. Amorphous solid. Yield 76%.

후처리

  1. temperaturewas refluxed for 14 hours
  2. temperatureAfter cooling
  3. filtrationthe solid precipitate was recovered by filtration

출처 및 근거

ORD 기록
ord-6f5f3deb684e4dc4b6e97db8d01c6841
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06248766B1

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