Benzyl Bromide → [(2-Benzylthio-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy]acetic acid

HRID 1067422

반응식

C([O:3][C:4](=[O:21])[CH2:5][O:6][C:7]1[CH:20]=[CH:19][CH:18]=[C:17]2[C:8]=1[CH2:9][CH2:10][C:11]1[S:15][C:14]([SH:16])=[N:13][C:12]=12)C.[CH2:22](Br)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:22]([S:16][C:14]1[S:15][C:11]2[CH2:10][CH2:9][C:8]3[C:17](=[CH:18][CH:19]=[CH:20][C:7]=3[O:6][CH2:5][C:4]([OH:3])=[O:21])[C:12]=2[N:13]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

참가 물질

반응물 2

HCID 7498Benzyl Bromide

HCID 178472952Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate

생성물 1

HCID 12050064[(2-Benzylthio-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy]acetic acid수율 44%

실험 절차

Using ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy]acetate and benzyl bromide, the procedure of Example 1 was otherwise repeated to synthesize the title compound. Yield 44%.

출처 및 근거

ORD 기록: ord-7d978782d5f24f87901eadffc9fac614
출처 데이터셋: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06248766B1

연결된 노트

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