(Bromomethyl)cyclopentane → 4-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile

반응식

[Br:30][CH2:31][CH:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[Cl:1][c:2]1[cH:3][c:4]([OH:29])[c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH2:13][c:14]2[c:15]([F:22])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:23][c:24]([F:28])[c:25]([F:27])[cH:26]3)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][c:4]([O:29][CH2:31][CH:32]2[CH2:33][CH2:34][CH2:35][CH2:36]2)[c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH2:13][c:14]2[c:15]([F:22])[cH:16][c:17]([C:18]#[N:19])[cH:20][cH:21]2)[cH:23][c:24]([F:28])[c:25]([F:27])[cH:26]3)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 12723264(Bromomethyl)cyclopentane

HCID 1363784944-[2-(4-Chloro-2-hydroxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile

생성물 1

HCID 670501034-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-3-fluoro-benzonitrile

출처 및 근거

ORD 기록: ord-5b85e2f3789947f9bec697530a0d430e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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