Water → Cyclopentadienyl-2-indenyl-dimethylsilane

HRID 1068059노트

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HRID 1068059 반응식
Cl[Si:2]([C:5]1[CH2:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2)([CH3:4])[CH3:3].[CH:14]1([Na])[CH:18]=[CH:17][CH:16]=[CH:15]1.O>C(OCC)C.O1CCCC1>[CH:14]1([Si:2]([C:5]2[CH2:6][C:7]3[C:12]([CH:13]=2)=[CH:11][CH:10]=[CH:9][CH:8]=3)([CH3:3])[CH3:4])[CH:18]=[CH:17][CH:16]=[CH:15]1

참가 물질

6

반응물 3

HCID 962WaterHCID 22395124Chloro(1H-inden-2-yl)dimethylsilaneHCID 178507085HCID 178507085, 화합물

생성물 1

HCID 131722676Cyclopentadienyl-2-indenyl-dimethylsilane수율 46%

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 8028Tetrahydrofuran용매

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온도
0 °C

실험 절차

Chloro-2-indenyldimethylsilane (4.6 g, 0.022 mol.) from Example 1 was dissolved in 20 ml of diethyl ether. The solution was cooled to 0° C., and a solution of cyclopentadienylsodium (1.94 g, 0.022 mol.) in 20 ml of tetrahydrofuran was added dropwise. The mixture was stirred for 15 hours at 25° C. 50 ml of water were then added, and the organic phase was washed with water again and dried over Na2SO4. After removal of the solvents under an oil pump vacuum, the light-yellow oil that remained was purified by means of column chromatography. The solvent was removed to yield 2.4 g (46%) of cyclopentadienyl-2-indenyl-dimethylsilane in the form of a colorless oil.

후처리

  1. washthe organic phase was washed with water again
  2. dry with materialdried over Na2SO4
  3. customAfter removal of the solvents under an oil pump vacuum
  4. customthe light-yellow oil that remained was purified by means of column chromatography
  5. customThe solvent was removed

출처 및 근거

ORD 기록
ord-197e2ae0a8af487e9547da2006281190
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06248912B1

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