Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 3-nitro-5-phenylbenzoate → Methyl 5-amino-[1,1'-biphenyl]-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 3-nitro-5-phenylbenzoate | HCID 69687208 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Methyl 5-amino-[1,1'-biphenyl]-3-carboxylate | HCID 67513694 | — |
반응 단계
5-Nitro-biphenyl-3-carboxylic acid methyl ester (1.85 g, 7.19 mmol) and 10% Pd/C (0.185 g) in EtOAc (20 mL) were hydrogenated under balloon for 2 h. The catalyst was filtered and the filtrate was concentrated to dryness. The crude 5-amino-biphenyl-3-carboxylic acid methyl ester was a yellow solid and was taken to the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06903086B2 |
| 출처 데이터셋 | uspto-grants-2005_06 |
| ORD ID | ord-e3e681e95c2d4e1c94cc267285ae05ee |
| 출처 메모 | uspto-grants-2005_06 |