Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trichloroisocyanuric Acid → Methyl 2-(chloromethyl)pyridine-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trichloroisocyanuric Acid | HCID 6909 | — |
| 반응물 | Methyl 2-methylnicotinate | HCID 7015327 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Methyl 2-(chloromethyl)pyridine-3-carboxylate | HCID 19081344 | 45.7% |
반응 단계
A solution of methyl 2-methylnicotinate (20.0 g, 0.132 mol) and trichloroisocyanuric acid (46.0 g, 0.198 mol) in dichloromethane (100 mL) was stirred at room temperature overnight. The reaction mixture was then washed with saturated aqueous sodium carbonate and saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate, filtered, and the solvent evaporated in vacuo to provide the title compound as a yellow liquid (11.2 g), which is used as such in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06903091B2 |
| 출처 데이터셋 | uspto-grants-2005_06 |
| ORD ID | ord-030aea0f86e740558a593b5da77d0876 |
| 출처 메모 | uspto-grants-2005_06 |