Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 2-(Pyrimidin-2-yloxy)acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Ethyl 2-pyrimidinyloxyacetate | HCID 22396258 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-(Pyrimidin-2-yloxy)acetic acid | HCID 566272 | 58.9% |
반응 단계
Ethyl 2-pyrimidinyloxyacetate (1.4 g) was dissolved in ethanol (10 ml). Sodium hydroxide (2M aq) was added and the mixture was stirred for 64 h. The solvent was evaporated and the residue was dissolved in water, filtered and the acidified with concentrated hydrochloric acid. The resulting precipitate was collected and dried to give the subtitle compound (0.698 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06903085B1 |
| 출처 데이터셋 | uspto-grants-2005_06 |
| ORD ID | ord-fde72d6116224d3081aa845e2d8ee2c7 |
| 출처 메모 | uspto-grants-2005_06 |