trans-2-Phenylcyclopropyl isocyanate → N-{3-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-N'-[(1R*,2S)-2-phenylcyclopropyl]urea

HRID 1070818

반응식

HRID 1070818 반응식
[C:1]1([C@@H:7]2[CH2:9][C@H:8]2[N:10]=[C:11]=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:13][CH2:14][CH2:15][CH2:16][N:17]1[C:25]2[C:24]([CH3:26])=[C:23]([CH3:27])[N:22]=[C:21]([NH2:28])[C:20]=2[N:19]=[C:18]1[CH2:29][O:30][CH2:31][CH3:32]>>[NH2:28][C:21]1[C:20]2[N:19]=[C:18]([CH2:29][O:30][CH2:31][CH3:32])[N:17]([CH2:16][CH2:15][CH2:14][NH:13][C:11]([NH:10][C@@H:8]3[CH2:9][C@H:7]3[C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[O:12])[C:25]=2[C:24]([CH3:26])=[C:23]([CH3:27])[N:22]=1

참가 물질

3

반응물 2

HCID 255285trans-2-Phenylcyclopropyl isocyanateHCID 219738361-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine

생성물 1

HCID 20575810N-{3-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-N'-[(1R*,2S)-2-phenylcyclopropyl]urea

실험 절차

Using the method of Examples 94-105, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 437.2674.

출처 및 근거

ORD 기록
ord-45f6a253f88b4a9d8cd2619d4e56cded
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06903113B2

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