Ethylamine → 29526-66-7

HRID 1071511노트

반응식

HRID 1071511 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-])=O.[CH2:14]([NH2:16])[CH3:15]>C(Cl)Cl>[NH2:11][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:2]=1[CH3:1])[C:6]([NH:16][CH2:14][CH3:15])=[O:7]

참가 물질

4

반응물 2

HCID 6341EthylamineHCID 663234-Methyl-3-nitrobenzoyl chloride

생성물 1

HCID 1260797429526-66-7

시약·촉매·용매 1

HCID 6344Dichloromethane용매

반응 조건

온도
0 °C

실험 절차

4-methyl-3-nitro-benzoyl chloride (1.0 g, 5.0 mmol) was dissolved in DCM, and the solution was cooled to 0° C. Ethyl amine (2.0 M in THF, 5.0 mL, 10 mmol) was added dropwise to the acid chloride, and the reaction stirred at 0° C. for 5 min. The ice bath was removed and reaction continued to stir for 3. The solution was washed with brine, dried (Na2SO4), and concentrated in vacuo. The resulting aniline (0.75 g) was used without further purification.

후처리

  1. customThe ice bath was removed
  2. customreaction
  3. stirringto stir for 3
  4. washThe solution was washed with brine
  5. dry with materialdried (Na2SO4)
  6. concentrationconcentrated in vacuo
  7. customThe resulting aniline (0.75 g) was used without further purification

출처 및 근거

ORD 기록
ord-2dff38dbaa724d6d8ccc0f12cda4885a
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06906067B2

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