1-(2-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}ethyl)piperazine → 1-[4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl]-4-[2-(5-trifluoromethyl-2-pyridyloxy)ethyl]piperazine
반응식
[C:1]([C:3]([C:11]1[S:12][C:13]([C:16]#[N:17])=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[F:18][C:19]([F:36])([F:35])[C:20]1[CH:21]=[CH:22][C:23]([O:26][CH2:27][CH2:28][N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)=[N:24][CH:25]=1>>[C:1]([C:3]([C:11]1[S:12][C:13]([C:16]#[N:17])=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:32]1[CH2:33][CH2:34][N:29]([CH2:28][CH2:27][O:26][C:23]2[CH:22]=[CH:21][C:20]([C:19]([F:36])([F:18])[F:35])=[CH:25][N:24]=2)[CH2:30][CH2:31]1)#[N:2]참가 물질
3
실험 절차
The title compound was synthesized in accordance with Example 77 from 4-cyano-4-(5-cyano-2-thienyl)-5-methylhexyl iodide and 1-[2-(5-trifluoromethyl-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.
출처 및 근거
- ORD 기록
- ord-2d6280af73ee4e43912e44628cf478d9
- 출처 데이터셋
- uspto-grants-2005_06
- 특허 번호
- US06906072B1
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