1-(2-((5-Chloropyridin-3-yl)oxy)ethyl)piperazine → 1-[4-Cyano-4-(5-cyano-2-thienyl)-5-methylhexyl]-4-[2-(5-chloro-3-pyridyloxy)ethyl]piperazine
반응식
[C:1]([C:3]([C:11]1[S:12][C:13]([C:16]#[N:17])=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[Cl:18][C:19]1[CH:20]=[C:21]([O:25][CH2:26][CH2:27][N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH:22]=[N:23][CH:24]=1>>[C:1]([C:3]([C:11]1[S:12][C:13]([C:16]#[N:17])=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:31]1[CH2:32][CH2:33][N:28]([CH2:27][CH2:26][O:25][C:21]2[CH:22]=[N:23][CH:24]=[C:19]([Cl:18])[CH:20]=2)[CH2:29][CH2:30]1)#[N:2]참가 물질
3
실험 절차
The title compound was synthesized in accordance with Example 77 from 4-cyano-4-(5-cyano-2-thienyl)-5-methylhexyl iodide and 1-[2-(5-chloro-3-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.
출처 및 근거
- ORD 기록
- ord-9b0bed690d4745dba49c9b4aa8ef24ba
- 출처 데이터셋
- uspto-grants-2005_06