Dicyclopentadiene → 1-Bromo-1,1,2,2-tetrafluoro-2-(tetracyclo[4.4.0.12,5.17,10]dodec-3-en-8-yl)ethane

HRID 1071892

반응식

HRID 1071892 반응식
[CH2:1]1[CH:5]2[CH:6]3[CH:10]=[CH:9][CH:8]([CH:4]2[CH:3]=[CH:2]1)[CH2:7]3.[Br:11][C:12]([F:19])([F:18])[C:13]([F:17])([F:16])[CH:14]=[CH2:15]>C1(C)C=CC=CC=1.COC1C=CC(O)=CC=1>[Br:11][C:12]([F:19])([F:18])[C:13]([F:17])([F:16])[CH:14]1[CH2:15][CH:1]2[CH2:2][CH:3]1[CH:4]1[CH:5]2[CH:6]2[CH2:7][CH:8]1[CH:9]=[CH:10]2

참가 물질

5

반응물 2

HCID 6492DicyclopentadieneHCID 877214-Bromo-3,3,4,4-tetrafluoro-1-butene

생성물 1

HCID 865884301-Bromo-1,1,2,2-tetrafluoro-2-(tetracyclo[4.4.0.12,5.17,10]dodec-3-en-8-yl)ethane수율 81.2%

시약·촉매·용매 2

HCID 90154-Methoxyphenol촉매HCID 1140Toluene용매

반응 조건

온도
170 °C

실험 절차

An autoclave was charged with 108.5 g of dicyclopentadiene and 322.4 g of 1-bromo-1,1,2,2-tetrafluoro-3-butene. A solution of 0.3 g of 4-methoxyphenol dissolved in 5 ml of toluene was added to the autoclave as a polymerization inhibitor and the mixture was stirred for 5 hours at 170° C. The reaction product was purified by distillation under reduced pressure at 85° C. and 0.1 mmHg to obtain 226 g of 1-bromo-1,1,2,2-tetrafluoro-2-(tetracyclo[4.4.0.12,5.17,10]dodec-3-en-8-yl)ethane as a clear liquid (hereinafter referred to as “compound (5-a)”).

후처리

  1. additionwas added to the autoclave as a polymerization inhibitor
  2. distillationThe reaction product was purified by distillation under reduced pressure at 85° C.

출처 및 근거

ORD 기록
ord-4d89429e7347461993982ff34ef27c2f
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06908722B2

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