Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → Benzidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 2-Nitrobenzenesulphonic acid | HCID 6664 | — |
| 반응물 | Nitrobenzene | HCID 7416 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Hydrazobenzene | HCID 31222 | — |
| 반응물 | Sodium 3-nitrobenzenesulfonate | HCID 31389 | — |
| 촉매 | Zinc | HCID 23994 | — |
| 생성물 | Benzidine | HCID 7111 | — |
반응 단계
A 2-nitrobenzenesulfonic acid derivative (e.g. sodium 2-nitrobenzenesulfonate) or a 3-nitrobenzenesuflonic acid derivative (e.g. sodium 3-nitrobenzenesulfonate) and nitrobenzene are treated with zinc dust in the presence of an alkali (e.g. sodium hydroxide) and the resulting hydrazobenzene derivative is treated with sulfuric acid, to give the corresponding 4,4′-diaminobiphenyl derivative. This is diazotized using sodium nitrite under acidic conditions in the presence of hydrochloric acid, followed by reaction with sodium azide, to give the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06908719B1 |
| 출처 데이터셋 | uspto-grants-2005_06 |
| ORD ID | ord-c9827427759e481e95f5eb7980b46efa |
| 출처 메모 | uspto-grants-2005_06 |