3,5-Dimethyl-1H-pyrrole-2-carbaldehyde → HCID 73885145, 화합물

HRID 1072143노트

반응식

HRID 1072143 반응식
[Cl:1][C:2]1[C:3]2[CH2:10][C:9](=[O:11])[NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:12][C:13]1[CH:17]=[C:16]([CH3:18])[NH:15][C:14]=1[CH:19]=O>>[Cl:1][C:2]1[C:3]2[C:10](=[CH:19][C:14]3[NH:15][C:16]([CH3:18])=[CH:17][C:13]=3[CH3:12])[C:9](=[O:11])[NH:8][C:4]=2[N:5]=[CH:6][N:7]=1

참가 물질

3

반응물 2

HCID 2704653,5-Dimethyl-1H-pyrrole-2-carbaldehydeHCID 120958704-chloro-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

생성물 1

HCID 73885145HCID 73885145, 화합물수율 44.5%

실험 절차

4-Chloro-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one (1 eq.) was condensed with 3,5-dimethyl-1H-pyrrole-2-carbaldehyde (1 eq.) at room temperature to give (44.5%) of 4-chloro-5-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one.

출처 및 근거

ORD 기록
ord-d55b8c95fe8d47829382ba61ddf470ae
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06908930B2

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