Cyclohexanecarbonyl chloride → Benzimidazole

HRID 1072535노트

반응식

NC1C=CC([C:8]2[NH:9][C:10]3[CH:16]=[CH:15][C:14](N)=[CH:13][C:11]=3[N:12]=2)=CC=1.C1(C(Cl)=O)CCCCC1>>[N:9]1[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[NH:12][CH:8]=1

참가 물질

반응물 2

HCID 75938Cyclohexanecarbonyl chloride

HCID 178507432HCID 178507432, 화합물

생성물 1

HCID 5798Benzimidazole

실험 절차

2-(N-Cyclohexylcarbonyl-4′-aminophenyl)-6-cyclohexylcarbonylamino)-benzimidazole was prepared by Method A from 2-(4-aminophenyl)-6-aminobenzimidazole (0.195 g, 0.87 mmole) and cyclohexylcarbonyl chloride (0.291 ml, 0.319 g, 2.175 mmole). The resulting solid (76.7 mg) was purified by preparative HPLC.

후처리

customThe resulting solid (76.7 mg) was purified by preparative HPLC

출처 및 근거

ORD 기록: ord-846edf29646848ffb9b26b83d99d7e9d
출처 데이터셋: uspto-grants-2005_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06911462B2

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