Acrylamide → 3-[3-(2-tert-Butoxycarbonylamino-2-methyl-propyl)-1H-indol-7-yl]-acrylamide
반응식
[C:1]([O:5][C:6](=[O:29])[NH:7][C:8]([CH3:28])([CH3:27])[CH2:9][C:10]1[C:18]2[C:13](=[C:14]([CH2:19]S(C(F)(F)F)(=O)=O)[CH:15]=[CH:16][CH:17]=2)[NH:12][CH:11]=1)([CH3:4])([CH3:3])[CH3:2].[C:30]([NH2:34])(=[O:33])[CH:31]=C>>[C:1]([O:5][C:6]([NH:7][C:8]([CH3:28])([CH3:27])[CH2:9][C:10]1[C:18]2[C:13](=[C:14]([CH:19]=[CH:31][C:30]([NH2:34])=[O:33])[CH:15]=[CH:16][CH:17]=2)[NH:12][CH:11]=1)=[O:29])([CH3:4])([CH3:3])[CH3:2]참가 물질
3
실험 절차
3-[3-(2-tert-Butoxycarbonylamino-2-methyl-propyl)-1H-indol-7-yl]-acrylamide is prepared from [1,1-dimethyl-2-(7-trifluoromethanesulfonylmethyl-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester and acrylamide as described for the preparation of Amine 23 (98%). FDMS m/e=356.2 (M++1).
출처 및 근거
- ORD 기록
- ord-8bfb0ac4433240e1b63cafac24042f06
- 출처 데이터셋
- uspto-grants-2005_06