2-(4-Benzyloxyphenyl)-5-methyl-1-(4-pentylphenylpropyl)-1H-pyrrole → 4-[5-Methyl-1-(4-pentylphenylpropyl)-1H-pyrrol-2-yl]phenol

HRID 1072718노트

반응식

HRID 1072718 반응식
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[N:16]([CH2:21][CH2:22][CH2:23][C:24]3[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=3)[C:17]([CH3:20])=[CH:18][CH:19]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1>C(O)C.[C].[Pd]>[CH3:20][C:17]1[N:16]([CH2:21][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=2)[C:15]([C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)=[CH:19][CH:18]=1

참가 물질

4

반응물 1

HCID 697319892-(4-Benzyloxyphenyl)-5-methyl-1-(4-pentylphenylpropyl)-1H-pyrrole

생성물 1

HCID 697326774-[5-Methyl-1-(4-pentylphenylpropyl)-1H-pyrrol-2-yl]phenol수율 54%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

To a solution of 2-(4-benzyloxyphenyl)-5-methyl-1-(4-pentylphenylpropyl)-1H-pyrrole (2.99 g, 6.6 mmol) in ethanol (60 ml) was added 10% palladium carbon (300 mg) and the mixture was stirred under hydrogen atmosphere. The insoluble matter was filtered out and the filtrate was concentrated to give the object compound as an oily substance. 1.28 g, (yield 54% )

후처리

  1. filtrationThe insoluble matter was filtered out
  2. concentrationthe filtrate was concentrated
  3. customto give the object compound as an oily substance

출처 및 근거

ORD 기록
ord-18ae5b44f76f4f6fa55d1553d4ba9813
출처 데이터셋
uspto-grants-2005_06
특허 번호
US06911468B2

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