Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4-methyl-2,7-diphenyl-1H-pyrazolo[3,4-b]pyridine-3,6-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | HCID 178516394 | HCID 178516394 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-methyl-2,7-diphenyl-1H-pyrazolo[3,4-b]pyridine-3,6-dione | HCID 360316 | 34.5% |
반응 단계
1-Phenyl-3-anilino-2-pyrazolin-5-one (25 g), ethyl acetoacetate (18 g) and acetic acid (150 ml) were refluxed with heating for 6 hours. The reaction solution was diluted while water, and the resulting solid was crystallized from acetonitrile to obtain 10.9 g of 2,7-diphenyl-4-methylpyrazolo(3,4-b)pyridine-3,6-dione. Melting point 145°-147° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04968593 |
| 출처 데이터셋 | uspto-grants-1990_11 |
| ORD ID | ord-a9b6fc767ff94906a396fad10d142e5f |
| 출처 메모 | uspto-grants-1990_11 |