참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 7-Chloro-2,3-dihydro-4-quinolone | HCID 88974 | — |
| 반응물 | 2-(Ethylthio)Nicotinoyl Chloride | HCID 2774534 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 7-chloro-l-(2-ethylthio-3-pyridylcarbonyl)-2,3-dihydro-4(lH)-quinolinone | HCID 22157978 | — |
반응 단계
To a mixture of 7-chloro-2,3-dihydro-4(lH)-quinolinone (25 g), pyridine (32 g) and dioxane (200 ml) was added dropwise 2-ethylthio-3-pyridylcarbonyl chloride (37 under cooling at 0 C. to 5° C. with stirring. The mixture was allowed to react at room temperature for additional 3 hours. The reaction mixture was subjected to the procedure described in example 1, and 43 g of 7-chloro-l-(2-ethylthio-3-pyridylcarbonyl)-2,3-dihydro-4(lH)-quinolinone was obtained as white crystal.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04968680 |
|---|
| 출처 데이터셋 | uspto-grants-1990_11 |
|---|
| ORD ID | ord-5c5615cdc391407fba391293e48e8d9b |
|---|
| 출처 메모 | uspto-grants-1990_11 |
|---|
