2-Dimethylaminopyridine → 2,4-Dichloro-6-methyloxybenzoyl chloride
반응식
[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[C:7]([O:12][CH3:13])[C:3]=1[C:4](O)=[O:5].CN(C1C=CC=CN=1)C.S(Cl)([Cl:25])=O>C(Cl)Cl>[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[C:7]([O:12][CH3:13])[C:3]=1[C:4]([Cl:25])=[O:5]참가 물질
5
실험 절차
26.0 g. (0.117 mol) 2,4-Dichloro-6-methoxybenzoic acid were dissolved in 50 ml. anhydrous methylene chloride and, after the addition of 0.1 g. dimethylaminopyridine, 50 ml. thionyl chloride were added dropwise thereto at ambient temperature. After stirring for 15 hours, the reaction mixture was evaporated and the residue distilled. Yield: 55% of theory; b.p. 118-124° C./0.1 mm.Hg.
후처리
- customat ambient temperature
- customthe reaction mixture was evaporated
- distillationthe residue distilled
출처 및 근거
- ORD 기록
- ord-54c91ab192824b9c8107ede9611926c7
- 출처 데이터셋
- uspto-grants-1990_11
- 특허 번호
- US04970077
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