Tributylstannane → 1-(tributylstannyl)-1E-undecen-3-ol

HRID 1073575노트

반응식

HRID 1073575 반응식
[CH:1]#[C:2][CH:3]([OH:12])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[CH2:13]([SnH:17]([CH2:22][CH2:23][CH2:24][CH3:25])[CH2:18][CH2:19][CH2:20][CH3:21])[CH2:14][CH2:15][CH3:16]>>[CH2:22]([Sn:17]([CH2:13][CH2:14][CH2:15][CH3:16])([CH2:18][CH2:19][CH2:20][CH3:21])/[CH:1]=[CH:2]/[CH:3]([OH:12])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:23][CH2:24][CH3:25]

참가 물질

3

반응물 2

HCID 5948TributylstannaneHCID 2477661-Undecyn-3-ol

생성물 1

HCID 121582911-(tributylstannyl)-1E-undecen-3-ol

반응 조건

온도
120 °C

실험 절차

To 0.07 g (0.42 mmol) of the titled product of Example 7 is added 0.15 g (0.5 mmol) of tri-n-butyltin hydride and 20 mg of azoisobutyronitrile (AIBN). The reaction mixture was heated to 120° C. for 2 hours. Afterwards, it was cooled to room temperature and pumped at high vacuum overnight. The crude reaction mixture was then heated to 90° C. and maintained at high vacuum for 2 additional hours. Upon cooling to room temperature, the crude product was used as is.

후처리

  1. temperatureAfterwards, it was cooled to room temperature
  2. custompumped at high vacuum overnight
  3. customThe crude reaction mixture
  4. temperaturewas then heated to 90° C.
  5. temperaturemaintained at high vacuum for 2 additional hours
  6. temperatureUpon cooling to room temperature

출처 및 근거

ORD 기록
ord-891c119b5cdd467fa48e49be0b0be73c
출처 데이터셋
uspto-grants-1990_11
특허 번호
US04970229

반응 노트

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