Morpholine → HCID 13175260, 화합물

HRID 1074388노트

반응식

HRID 1074388 반응식
Cl[C:2]1[CH:14]=[CH:13][C:5]2=[N:6][C:7]3[CH2:12][CH2:11][CH2:10][CH2:9][C:8]=3[N:4]2[N:3]=1.[NH:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1>>[N:15]1([C:2]2[CH:14]=[CH:13][C:5]3=[N:6][C:7]4[CH2:12][CH2:11][CH2:10][CH2:9][C:8]=4[N:4]3[N:3]=2)[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

참가 물질

3

반응물 2

HCID 8083MorpholineHCID 11148455HCID 11148455, 화합물

생성물 1

HCID 13175260HCID 13175260, 화합물

실험 절차

A mixture was prepared by adding 5.0 g of 2-chloro-6,7,8,9-tetrahydropyridazino[1,6-a]benzimidazole to 30 ml of morpholine and this was stirred and heated at reflux for 24 hours. It was then poured into 200 ml of ice water. A tan solid formed and this was separated by filtration to give 2-(4-morpholinyl)-6,7,8,9-tetrahydropyridazino[1,6-a]benzimidazole melting at 187.5°-188.5° C.

후처리

  1. customA mixture was prepared
  2. temperatureheated
  3. temperatureat reflux for 24 hours
  4. customA tan solid formed
  5. customthis was separated by filtration

출처 및 근거

ORD 기록
ord-dc5e57af1b4a498394618e559a8fb055
출처 데이터셋
uspto-grants-1983_07
특허 번호
US04391806

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