Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Levulinic Acid → 1-(3'-Amino-4',6'-dimethylphenyl)-5-methyl-pyrrolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Levulinic Acid | HCID 11579 | — |
| 반응물 | 4,6-Diamino-1,3-m-xylene | HCID 854386 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Platinum oxide (PtO) | HCID 82844 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(3'-Amino-4',6'-dimethylphenyl)-5-methyl-pyrrolidin-2-one | HCID 12833274 | 80% |
반응 단계
A suspension of 0.2 g of platinum oxide in 25 ml of ethanol is treated with hydrogen and a solution of 34.8 g (0.3 mol) of levulinic acid and 85 g (0.62 mol) of 3-amino-4,6-dimethylaniline in 300 ml of ethanol is then added. The hydrogenation is carried out at room temperature. The desired pyrrolidinone derivative is obtained in a yield of about 80%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04394156 |
| 출처 데이터셋 | uspto-grants-1983_07 |
| ORD ID | ord-dc3c4e10beef4146bfdccf5ba09316b3 |
| 출처 메모 | uspto-grants-1983_07 |