Acetone → 5-Chloro-1-(prop-2-en-1-yl)pyrimidin-2(1H)-one

HRID 1075149노트

반응식

[Cl:1][C:2]1[CH:3]=[N:4][C:5](=[O:8])[NH:6][CH:7]=1.[CH3:9][C:10]([CH3:12])=O>>[CH2:12]([N:4]1[CH:3]=[C:2]([Cl:1])[CH:7]=[N:6][C:5]1=[O:8])[CH:10]=[CH2:9]

참가 물질

반응물 2

HCID 180Acetone

HCID 1085785-Chloro-2(1H)-pyrimidinone

생성물 1

HCID 126485265-Chloro-1-(prop-2-en-1-yl)pyrimidin-2(1H)-one수율 64%

실험 절차

1-Allyl-5-chloropyrimid-2-one was prepared from 5-chloropyrimid-2-one as above in 64% yield. m.p. 130°-131° C. (acetone) (Found: C, 49.22; H, 4.13. Calc. for C7H7ClN2O: C, 49.28; H, 4.13).

출처 및 근거

ORD 기록: ord-d451c9241c8547ee8843c24bb3480d99
출처 데이터셋: uspto-grants-1983_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04395406

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