Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Toluenesulfonyl chloride → N-Benzyl-3,4-dimethoxyamphetamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | 3,4-Dimethoxy-alpha-methylbenzeneethanol | HCID 89187 | — |
| 생성물 | N-Benzyl-3,4-dimethoxyamphetamine | HCID 410200 | — |
반응 단계
The 1-(3,4-dimethoxyphenyl)-2-propanol obtained above was subjected to sulfonylation by p-toluenesulfonyl chloride and reacted with benzylamine to give N-benzyl-3,4-dimethoxyamphetamine. The resultant compound was converted into 3,4-dimethoxyamphetamine by hydrogenation decomposition under hydrogen atmosphere with 5% Pd-C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05902900 |
| 출처 데이터셋 | uspto-grants-1999_05 |
| ORD ID | ord-028b640de99046ed98364198a9c82c25 |
| 출처 메모 | uspto-grants-1999_05 |