N-((Phenylmethoxy)carbonyl)-L-alanyl-L-alanine → N-[2-(N-Carbobenzoxy-L-alanyl-L-alanyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-dodecanamide

HRID 1075598

반응식

HRID 1075598 반응식
[NH2:1][CH2:2][C:3]([C@@H:5]1[C@@H:10]([OH:11])[C@H:9]([OH:12])[C@@H:8]([CH2:13][OH:14])[O:7][C@@:6]1([NH2:43])[N:15]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:16](=[O:28])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[O:4].[C:44]([NH:54][C@H:55]([C:57]([NH:59][C@H:60]([C:62](O)=[O:63])[CH3:61])=[O:58])[CH3:56])([O:46][CH2:47][C:48]1[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=1)=[O:45]>O1CCCC1>[C:44]([NH:54][C@H:55]([C:57]([NH:59][C@H:60]([C:62]([NH:1][CH2:2][C:3]([C@@H:5]1[C@@H:10]([OH:11])[C@H:9]([OH:12])[C@@H:8]([CH2:13][OH:14])[O:7][C@@:6]1([NH2:43])[N:15]([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:16](=[O:28])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[O:4])=[O:63])[CH3:61])=[O:58])[CH3:56])([O:46][CH2:47][C:48]1[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=1)=[O:45]

참가 물질

4

반응물 2

HCID 7009583N-((Phenylmethoxy)carbonyl)-L-alanyl-L-alanineHCID 131721235N-(2-glycyl-amino-2-deoxy-beta-D-glucopyranosyl)-N-tetradecyl-dodecanamide

생성물 1

HCID 131721244N-[2-(N-Carbobenzoxy-L-alanyl-L-alanyl-glycyl)-amino-2-deoxy-beta-D-glucopyranosyl]-N-tetradecyl-dodecanamide수율 70%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

from N-(2-glycyl-amino-2-deoxy-β-D-glucopyranosyl)-N-tetradecyl-dodecanamide and N-carbobenzoxy-L-alanyl-L-alanine. Yield 70%. [α]D =+10.3° (c=0.92, tetrahydrofuran). m.p. 99-100°.

출처 및 근거

ORD 기록
ord-7fae4727683741af9c52de7f61e8fa20
출처 데이터셋
uspto-grants-1999_05
특허 번호
US05905071

연결된 노트

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