6,15-diketo-13,14-dihydroprostaglandin F1alpha → Pga1

HRID 1075617

반응식

[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][C@H:6]([OH:24])/[CH:7]=[CH:8]/[C:9]1[CH2:14][CH2:13][C:11](=[O:12])[C:10]=1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([OH:23])=[O:22].CCCCC[C@H](O)/C=C/[C@H]1C(=O)C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O.CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](CCCCCCC(O)=O)[C@@H](O)C[C@H]1O.CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C[C@H]1O.CCCCCC(/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C[C@H]1O)=O.CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](CC(CCCCC(O)=O)=O)[C@@H](O)C[C@H]1O.CC(OC(CCC/C=C\C[C@@H]1[C@@H](CC[C@@H](O)CCC2C=CC=CC=2)[C@H](O)C[C@@H]1O)=O)C.CCCCCC(CC[C@@H]1[C@@H](CC(CCCCC(O)=O)=O)[C@@H](O)C[C@H]1O)=O.CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](CCCCCCC(O)=O)[C@H](O)C[C@H]1O.CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@H](O)C[C@H]1O.CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C[C@@H]1O.CCCCC[C@H](O)/C=C/[C@H]1C(=O)C=C[C@@H]1C/C=C\CCCC(O)=O>>[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][C@H:6]([OH:24])/[CH:7]=[CH:8]/[C@@H:9]1[C@@H:10]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([OH:23])=[O:22])[C:11](=[O:12])[CH:13]=[CH:14]1

참가 물질

반응물 12

HCID 1740136,15-diketo-13,14-dihydroprostaglandin F1alpha

HCID 448457Prostaglandin D2

HCID 5280363Dinoprost

HCID 5280388Pgb1

HCID 5280884Pgj2

HCID 528088611-Epiprostaglandin F2alpha

HCID 528088715-keto-PGF2alpha

HCID 52808886-Ketoprostaglandin F1 alpha

HCID 5280939PGF1alpha

HCID 5283070Prostaglandin F1beta

HCID 52832168-iso-PGF2beta

HCID 5311221Latanoprost

생성물 1

HCID 5281912Pga1

실험 절차

Prostaglandins which have been determined to be ineffective or have a low effectiveness in stimulating melanogenesis in melanocytes include: PGB1 ; PGD2 ; PGF1α ; PGF2α ; 15-keto PGF2α ; 6-keto PGF1α ; Latanoprost; 6,15-diketo-13,14-dihydro PGF1α ; 8-iso PGF1β ; 8-iso PGF2β ; 11β-PGF1β ; 11β-PGF2α ; and PGJ2.

출처 및 근거

ORD 기록: ord-d69eb529d5fd4ec7a337919facc9b591
출처 데이터셋: uspto-grants-1999_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05905091

연결된 노트

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