Triethylamine → HCID 54342534, 화합물

HRID 1076189노트

반응식

HRID 1076189 반응식
[NH:1]=[C:2]1[N:6]=[C:5]([N:7]([CH3:9])[CH3:8])[S:4][S:3]1.[C:10]([N:14]=[C:15]=[O:16])([CH3:13])([CH3:12])[CH3:11].C(N(CC)CC)C>O1CCCC1>[C:10]([NH:14][C:15]([N:1]=[C:2]1[N:6]=[C:5]([N:7]([CH3:9])[CH3:8])[S:4][S:3]1)=[O:16])([CH3:13])([CH3:12])[CH3:11]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 62412tert-Butyl isocyanateHCID 215392483-imino-5-dimethylamino-3H-1,2,4-dithiazole

생성물 1

HCID 54342534HCID 54342534, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A suspension of 4.75 parts of the hydrobromide salt of 3-imino-5-dimethylamino-3H-1,2,4-dithiazole, two parts of t-butyl isocyanate, two parts of triethylamine, and 50 parts of tetrahydrofuran was stirred and refluxed for two days. The reaction mixture was cooled and the insoluble triethylammonium bromide was removed by filtration and discarded. The filtrate was then evaporated under reduced pressure leaving a white solid, which was recrystallized from isopropanol to afford 3.4 parts of 1-t-butyl-3-(5-dimethylamino-3H-1,2,4-dithiazol-3-ylidene)urea, m.p. 174°-177°C. dec.

후처리

  1. temperaturerefluxed for two days
  2. temperatureThe reaction mixture was cooled
  3. customthe insoluble triethylammonium bromide was removed by filtration
  4. customThe filtrate was then evaporated under reduced pressure
  5. customleaving a white solid, which
  6. customwas recrystallized from isopropanol

출처 및 근거

ORD 기록
ord-28ba2993189e456fb673467b2f17fa9c
출처 데이터셋
uspto-grants-1976_05
특허 번호
US03956303

반응 노트

불러오는 중…