Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → 4p-Chlorophenyl-5-methyl-2-pyrrolidinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | Nitroethane | HCID 6587 | — |
| 반응물 | Benzyltrimethylammonium hydroxide | HCID 66854 | — |
| 반응물 | 2-Propenoic acid, 3-(4-chlorophenyl)-, ethyl ester | HCID 201471 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4p-Chlorophenyl-5-methyl-2-pyrrolidinone | HCID 12395318 | — |
반응 단계
A mixture of 150 g. (2 mole) of nitroethane, 105 g. (0.5 mole) of ethyl-p-chlorocinnamate and 6.6 g. of Triton B (a 35% solution of trimethyl-benzyl-ammonium hydroxide in methanol) is heated for 20 hours at 80°C. After the reaction has finished, toluene is added, washing is carried out with a saturated solution of sodium chloride and the organic solution is dried and evaporated to dryness and the residue is distilled. Yield: 80%; B.P.: 150°-155°C./0.3 mm.Hg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03956314 |
| 출처 데이터셋 | uspto-grants-1976_05 |
| ORD ID | ord-faaf505d44704321a69020ba2cb9a13a |
| 출처 메모 | uspto-grants-1976_05 |