Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylate → tert-Butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}3-[1-(3-methoxypropyl)-2-oxo-1,2-dihydroquinolin-7-ylmethoxy]piperidine-1-carboxylate

반응식

[Cl:35][CH2:36][c:37]1[cH:38][cH:39][c:40]2[cH:41][cH:42][c:43](=[O:52])[n:44]([CH2:47][CH2:48][CH2:49][O:50][CH3:51])[c:45]2[cH:46]1.[OH:1][CH:2]1[CH2:3][N:4]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][c:20]2[c:21]([O:26][CH3:27])[cH:22][cH:23][cH:24][cH:25]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][c:20]2[c:21]([O:26][CH3:27])[cH:22][cH:23][cH:24][cH:25]2)[cH:12][cH:13]1)[CH2:36][c:37]1[cH:38][cH:39][c:40]2[cH:41][cH:42][c:43](=[O:52])[n:44]([CH2:47][CH2:48][CH2:49][O:50][CH3:51])[c:45]2[cH:46]1

참가 물질

반응물 2

HCID 15546933Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylate

HCID 684975367-chloromethyl-1-(3-methoxypropyl)-1H-quinolin-2-one

생성물 1

HCID 68571013tert-Butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}3-[1-(3-methoxypropyl)-2-oxo-1,2-dihydroquinolin-7-ylmethoxy]piperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-aec539439fb140d696c9b29e9ee22303
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…