Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → 5-Methoxy-2-[4-(2-chloroethoxy)anilino]benzothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | 4-(2-Chloroethoxy)aniline | HCID 119699 | — |
| 반응물 | 5-Methoxy-2-methylsulphonylbenzothiazole | HCID 21538596 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Methoxy-2-[4-(2-chloroethoxy)anilino]benzothiazole | HCID 21538599 | — |
반응 단계
A mixture of 5-methoxy-2-methylsulphonylbenzothiazole (1,105 g.), 4-(2-chloroethoxy)aniline (780 g.) and toluene (5 liters) is boiled for 2 hours under reflux with simultaneous removal of water. A further quantity of 4-(2-chloroethoxy)aniline (156 g.) is then added and the mixture boiled under reflux for 4 hours. The mixture is cooled, the solid filtered off, washed with ethanol (about 3 liters) and dried to give 5-methoxy-2-[4-(2-chloroethoxy)anilino]benzothiazole m.p. 176°- 178°C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03957999 |
| 출처 데이터셋 | uspto-grants-1976_05 |
| ORD ID | ord-14321e5b384c4a38ab4355a3ded5816b |
| 출처 메모 | uspto-grants-1976_05 |