Bromine → 4-Bromo-5,6,7,8-tetrahydronaphthalen-1-ol

HRID 1076872노트

반응식

HRID 1076872 반응식
[C:1]1([OH:11])[C:10]2[CH2:9][CH2:8][CH2:7][CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[Br:12]Br>C(Cl)(Cl)(Cl)Cl>[Br:12][C:4]1[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[C:1]([OH:11])=[CH:2][CH:3]=1

참가 물질

4

반응물 2

HCID 24408BromineHCID 682585,6,7,8-Tetrahydro-1-naphthol

생성물 1

HCID 222364764-Bromo-5,6,7,8-tetrahydronaphthalen-1-ol수율 22.9%

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매2회

실험 절차

To a solution of 37 grams (0.25 mole) of 5,6,7,8-tetrahydronaphthol in 150 ml of carbon tetrachloride was added dropwise with stirring a solution of 44 grams (0.25 mole) of bromine in 50 ml of carbon tetrachloride. When the addition was complete the mixture was stirred for 30 minutes at room temperature and then evaporated in vacuo to a residue which after two recrystallizations from hexane provided 13 grams (22.9 percent) of product, m.p. 83°-85°C.

후처리

  1. additionWhen the addition
  2. customevaporated in vacuo to a residue which
  3. customafter two recrystallizations from hexane

출처 및 근거

ORD 기록
ord-09abc6cc51ff4f11b20e62d4f0683c3b
출처 데이터셋
uspto-grants-1976_05
특허 번호
US03958006

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