Pyridine → 2-Methyl-1,3-cyclohexanedione

HRID 1077134

반응식

HRID 1077134 반응식
C(N(CC)CCC(=O)CCCC1C=CC=[C:12]([O:16]C)[CH:11]=1)C.[O:21]=N.N1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>C1C=CC=CC=1>[CH3:24][CH:25]1[C:12](=[O:16])[CH2:11][CH2:28][CH2:27][C:26]1=[O:21]

참가 물질

4

반응물 2

HCID 1049PyridineHCID 86733483Ketoamine 1-diethylamino-6-m-methoxyphenylhexan-3-one

생성물 1

HCID 709452-Methyl-1,3-cyclohexanedione

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

Add to the crude undistilled ketoamine 1-diethylamino-6-(m-methoxyphenyl)hexan-3-one (2.3 g), the material obtained by hydration of the acetylenic amine, 2-methylcyclohexane-1,3-dione (1 g), pyridine (1 cc) and benzene (12 cc), and reflux the mixture for 15 hours. Cool the mixture and filter off unreacted dione, add a little ether to the filtrate, and wash the ethereal solution with acid, and then water, and dry. Evaporate the solvents to obtain as residue crude 2-(6-m-methoxyphenyl-3-oxohexyl)-2-methylcyclohexane-1,3-dione (1.7 g).

출처 및 근거

ORD 기록
ord-b45269aaa8fc48aeb8e949d74a9cf1a2
출처 데이터셋
uspto-grants-1976_05
특허 번호
US03959322

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