3-Heptanone → 2-Ethylcyclopentane-1,3-dione

HRID 1077139

반응식

HRID 1077139 반응식
COC1C=[C:5]([CH:9](C)[CH2:10][CH2:11][C:12](=[O:15])C=C)[CH:6]=[CH:7]C=1.CCC(=[O:24])CCCC>[OH-].[K+]>[CH2:6]([CH:5]1[C:9](=[O:24])[CH2:10][CH2:11][C:12]1=[O:15])[CH3:7]

참가 물질

4

반응물 2

HCID 78023-HeptanoneHCID 21485611HCID 21485611, 화합물

생성물 1

HCID 699782-Ethylcyclopentane-1,3-dione

시약·촉매·용매 1

HCID 14797Potassium Hydroxide용매

실험 절차

Reflux a mixture of 6-(m-methoxyphenyl)hept-1-en-3-one and 1-diethylamino-6-)m-methoxypheyl)heptan-3-one (10 g, obtained by slow distillation of the latter substance) with 2-ethylcyclopentane-1,3-dione (7g) in 0.12% methanolic potassium hydroxide solution (40 cc) for 15 hours. Remove most of the methanol under reduced pressure and add a mixture of equal volumes or ether and benzene (50 cc). Wash the solution with 5% aqueous sodium hydroxide, water, 10% hydrochloric acid, and brine, and dry. Evaporate the solvent to leave as residue the triketone adduct 2-(6-m-methoxyphenyl-3-oxoheptyl)-2-ethylcyclopentane-1,3-dione (14 g); infrared absorption peak at 5.80 μ.

후처리

  1. temperatureReflux

출처 및 근거

ORD 기록
ord-7233eeb50d4248868cefed021bdaaa45
출처 데이터셋
uspto-grants-1976_05
특허 번호
US03959322

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