Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(3-Chlorophenyl)prop-2-enoic acid → (E)-8-(3-Chlorostyryl)-1,3-diethylxanthine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(3-Chlorophenyl)prop-2-enoic acid | HCID 74631 | — |
| 반응물 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 생성물 | (E)-8-(3-Chlorostyryl)-1,3-diethylxanthine | HCID 6448908 | 42.1% |
반응 단계
Substantially the same procedure as in Reference Example 70 was repeated using 3.50 g (17.7 mmol) of 5,6-diamino-1,3-diethyluracil and 3.55 g (19.4 mmol) of 3-chlorocinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.57 g (yield 42%) of Compound 131 as white plates.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05543415 |
| 출처 데이터셋 | uspto-grants-1996_08 |
| ORD ID | ord-1da7292b2dd14eb58ada6b1a106e9a7b |
| 출처 메모 | uspto-grants-1996_08 |