2-(4-(4-Nitrophenyl)piperazin-1-yl)ethanol → 4-(2-Hydroxyethyl)-1-(4-isothiocyanatophenyl)piperazine

HRID 10781

반응식

HRID 10781 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][OH:18])[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-])=O.[N-]=[C:20]=[S:21]>>[OH:18][CH2:17][CH2:16][N:13]1[CH2:14][CH2:15][N:10]([C:7]2[CH:8]=[CH:9][C:4]([N:1]=[C:20]=[S:21])=[CH:5][CH:6]=2)[CH2:11][CH2:12]1

참가 물질

3

반응물 2

HCID 27639362-(4-(4-Nitrophenyl)piperazin-1-yl)ethanolHCID 178418790HCID 178418790, 화합물

생성물 1

HCID 99651254-(2-Hydroxyethyl)-1-(4-isothiocyanatophenyl)piperazine

실험 절차

This compound was prepared from 4-(4-nitrophenyl)-1-piperazine-ethanol (Bionet Research Ltd.) using the hydrogenation and isothiocyanate-forming reactions used in Example 4.

후처리

  1. customforming reactions

출처 및 근거

ORD 기록
ord-63144ce9652240199f91e9d2e6bc1107
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094896B2

연결된 노트

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