Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuryl chloride → (2E)-2-[2-(4-chlorophenoxy)phenyl]-2-methoxyimino-N-methylacetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 반응물 | (2E)-2-methoxyimino-N-methyl-2-(2-phenoxyphenyl)acetamide | HCID 5483872 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (2E)-2-[2-(4-chlorophenoxy)phenyl]-2-methoxyimino-N-methylacetamide | HCID 19429863 | 68.1% |
반응 단계
A solution of (E)-N-methyl-2-(2-phenoxyphenyl)-2-methoxyiminoacetamide (500 mg) in dichloromethane was cooled to 0° C., and sulfuryl chloride (285 mg) was dropwise added thereto. The resultant mixture was stirred at the same temperature for 2 hours, diluted with water and extracted with diethyl ether. The solvent was dried and removed, and the residue was subjected to HPLC with a mixture of hexane and ethyl acetate to give 382 mg of the objective compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05548078 |
| 출처 데이터셋 | uspto-grants-1996_08 |
| ORD ID | ord-0e14e4fae84e4d0694823c9fa2d761c5 |
| 출처 메모 | uspto-grants-1996_08 |