Neopentylamine → HCID 19428493, 화합물

반응식

Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[C:4]([NH:9][CH2:10][C:11]([CH3:14])([CH3:13])[CH3:12])[N:3]=1.[NH2:15][CH2:16][C:17]([CH3:20])([CH3:19])[CH3:18]>>[Cl:8][C:6]1[CH:7]=[C:2]([NH:15][CH2:16][C:17]([CH3:20])([CH3:19])[CH3:18])[N:3]=[C:4]([NH:9][CH2:10][C:11]([CH3:14])([CH3:13])[CH3:12])[N:5]=1

참가 물질

반응물 2

HCID 79882Neopentylamine

HCID 19428516HCID 19428516, 화합물

생성물 1

HCID 19428493HCID 19428493, 화합물수율 49.4%

실험 절차

The reaction of 4,6-dichloro-2-(2,2-dimethylpropylamino)pyrimidine with 1-amino-2,2-dimethylpropane as described in Example 10 affords the title product in a yield of 49.4%, m.p.: 95°-98° C.

출처 및 근거

ORD 기록: ord-25e297d75f94476f807d5b1b17191ec8
출처 데이터셋: uspto-grants-1996_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05550240

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