Taurine → Magnesium taurate

HRID 1080571노트

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HRID 1080571 반응식
[OH-].[Mg+2:2].[OH-].[NH2:4][CH2:5][CH2:6][S:7]([OH:10])(=[O:9])=[O:8]>O.CO>[CH2:5]([NH2:4])[CH2:6][S:7]([O-:10])(=[O:9])=[O:8].[CH2:5]([NH2:4])[CH2:6][S:7]([O-:10])(=[O:9])=[O:8].[Mg+2:2]

참가 물질

5

반응물 2

HCID 1123TaurineHCID 73981Magnesium Hydroxide

생성물 1

HCID 13343447Magnesium taurate

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

A mixture of magnesium hydroxide (433 mg, 7.46 mmol; Aldrich) and taurine (1.87 g, 14.9 mmol) in 20 ml water was heated under reflux for seven hours. The resulting milky mixture was allowed to cool, diluted with 40 ml methanol and allowed to stand overnight at room temperature. A white powder, consisting mostly of magnesium taurate complex, was removed by filtration. The clear filtrate was concentrated under vacuum to a pasty slurry, then diluted slowly with 10 ml methanol. After 2 hours, crystalline magnesium taurate salt was obtained by filtration. The yield was 940 mg (41%). The melting point (decomposition) was about 300° C. This salt was identical to that obtained in Example 2.

후처리

  1. temperaturewas heated
  2. temperatureunder reflux for seven hours
  3. temperatureto cool
  4. customwas removed by filtration
  5. concentrationThe clear filtrate was concentrated under vacuum to a pasty slurry
  6. additiondiluted slowly with 10 ml methanol
  7. waitAfter 2 hours

출처 및 근거

ORD 기록
ord-e2c838754e514db8a07e152677df0951
출처 데이터셋
uspto-grants-1996_12
특허 번호
US05582839

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