Trifluoroacetic acid → Diethyl (4-{[4-{[4-fluoro-2-(methylcarbamoyl)phenyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-3-methoxybenzyl)phosphonate

반응식

[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48].[NH2:30][c:31]1[c:32]([C:33](=[O:34])[NH:35][CH3:36])[cH:37][c:38]([F:41])[cH:39][cH:40]1>>[c:2]1([NH:30][c:31]2[c:32]([C:33](=[O:34])[NH:35][CH3:36])[cH:37][c:38]([F:41])[cH:39][cH:40]2)[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]